Degenerative suspensory ligament desmitis (DSLD) - equine systemic proteoglycan accumulation (ESPA) 🔍

Desmite dégénérative du ligament suspenseur
"Il faut distinguer la desmite causée par un traumatisme, de la desmite dégénérative. La desmite dégénérative du ligament suspenseur est une affection chronique dégénérative uni- ou bilatérale du ligament suspenseur du boulet des membres antérieurs et postérieurs qui s’aggrave lentement et progressivement. Il s’agit probablement d’une affection systémique"

"Degenerative suspensory ligament desmitis, commonly called DSLD, also known as equine systemic proteoglycan accumulation (ESPA), is a systemic disease of the connective tissue of the horse and other equines. It is a disorder akin to Ehlers–Danlos syndrome being researched in multiple horse breeds. Originally thought to be a condition of overwork and old age, the disease is now recognized as hereditary and has been seen in horses of all ages, including foals. The latest research (2010) has led to the proposed renaming of the disease from DSLD to ESPA because of the systemic and hereditary components now being found.[1][2]

It has been found in many horse breeds, including Arabians, Thoroughbreds, American Quarter Horses, Morgans, Peruvian Pasos, Paso Finos, American Saddlebreds, several breeds of warmblood, Appaloosas, Friesians, Missouri Fox Trotters, Tennessee Walkers, American Paint Horses, National Show Horses, and Mustangs, as well as crossbreds and mules.

DSLD was once considered a condition of the legs only, as one of the most visible signs is when the fetlocks, particularly on the hind legs, collapse into a "coon-footed" position. However, microscopic examination in necropsy has shown DSLD horses can not only be affected in the tendons and ligaments of all legs and the patella, but can have affected tissues in the nuchal ligament, eyes, aorta, skin and fascia, lungs and other organs, as well as ligaments and tendons throughout the body. Because of its systemic nature, and because connective tissue is present everywhere in a biological entity, the entire body becomes affected in multiple ways as the disease progresses. Some horses have shown an iron overload in the liver as well."

What is DSLD?

Information and management for owners of DSLD/ESPA affected horses
Symptoms, diagnosis and management (9 page PDF)

Dr Kellon's Treatment Study for DSLD/ESPA horses (AAKG & JIAOGULAN)

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